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7th International Symposium on Recent
Advances in Environmental Health Research
Marriott Hotel, Jackson, MS, USA
September 12-15, 2010 |
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New Frontiers in Environmental
Health Research:
The causes of most human diseases
have been attributed to the complex
interactions between genetic factors
and environmental exposures. Hence,
control and prevention measures
highly rely on the understanding of
the cause and effect relationships
between these factors and disease
development. In recent years, new
areas of research such as
toxicogenomics, proteomics, and
functional genomics have emerged,
with the aim of understanding
molecular mechanisms of health and
disease. Also, the recent advances
in the molecular biology of the cell
cycle regulation have given new life
to our understanding of cancer in
particular, and the idea that
defects of regulation in cancer
cells may partially explain
successes that have been achieved in
cancer chemotherapy. Specific areas
of symposium research presentations
included gene expression studies,
proteomics, gene-environment
interactions, functional genomics,
biomarkers of effect, sensitivity
and effect, signal transduction and
gene activation; and molecular
targets of disease chemotherapy.
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Nanoscience, Nanotechnology &
Nanotoxicology:
In recent
years, nanoscience and
nanotechnology have gained a great
deal of public interest due to the
needs and applications of
nanomaterials in almost all areas of
human endeavors including industry,
agriculture, business, medicine and
public health. Hence, nanoscience
and nanotechnology rank among the
most prominent and rapidly emerging
fields that have provided
opportunities to individuals with
various academic backgrounds
(chemists, biologists, physicist,
material scientists, engineers,
medical specialists and
toxicologists) and scientific
expertise to understand things on
the nanoscale. While there have been
significant advances in nanoscience
and nanotechnology, there have been
concerns that the wide production
and utilization of nanomaterials is
rapidly overtaking efforts to
evaluate their toxicity to humans
and the environment. To date, very
few studies have focused on the
evaluation of the impact of
nanomaterials on human health.
Limited toxicological data indicate
that nanomaterials exposure poses a
potential risk to biological
systems. Symposium presentations
will focus on the toxicological and
health effects of nanomaterials
including single and multiwalled
carbon nanotudes, and quantum dots,
as well as on the application of
nanomaterials in biotechnology.
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Environmental Toxicology and
Health Risk Assessment:
Growing public awareness of the
potential risk to humans from toxic
chemicals in the environment has
generated demand for new and
improved methods for toxicity
assessment and rational means for
estimating health risk. Many
environmental agents such as metal
ions, polycyclic aromatic
hydrocarbons, pesticides/herbicides,
UV-light, food additives, and
viruses are known to induce various
types of illnesses including cancer
in humans. Several symposium
presentations dealt with research
elucidating the cellular and
molecular mechanisms by which these
environmental agents induce
toxicity, mutagenesis, and
carcinogenesis, as well as research
on hazard assessment of exposure to
physical, chemical and biological
agents; dose-response evaluation and
model development; exposure
assessment analysis; and health risk
characterization; and management.
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Emerging Topics in Computational
Biology, and Environmental Modeling:
Using of computational methods and
procedures to investigate
environmental and biological
phenomena has made remarkable
progresses. This field includes
analysis of human genome data,
prediction of DNA and protein
structure and function, design of
biomaterials and therapeutic agents,
studies into small molecule-biomacromolecule
interactions, and other related
computational method development.
Therefore, several symposium
presentations dealt with the
computational analysis of the
physical and chemical properties of
several environmental compounds, as
well as on quantitative structure
activity relationship (QSAR) studies
for developing predictive toxicology
models associated with exposure to
these compounds.
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Health Disparities and
Environmental Security:
In recent years health disparities
and biological and chemical
terrorism have emerged as major
issues in public safety and homeland
security. With recent advances in
laboratory technologies, it is often
possible to measure specific genetic
variations as risk factors for
specific types of disease. Equally
important is the evaluation of the
role of modifier factors such as
environmental exposures or other
genes that may exacerbate the
genetic risk leading to differences
in disease susceptibility among
individuals. Since the events of
September 11, 2001 regarding the
attacks on the World Trade Center
and the Pentagon, and the subsequent
anthrax attacks on several people,
our collective thinking with regard
to our vulnerability to terrorism
has completely changed. The specific
areas of research presentations
included the following: health
disparities and cancer; health
disparities and heart disease;
health disparities and infectious
diseases; and bioterrorism/chemical
terrorism.
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Medical Geology and Human
Health:
Recent concerns over health-related
issues arising from exposure to
environmental substances have raised
substantial interest in a new field
termed “medical geology”. In fact,
naturally occurring toxic metals
such as arsenic, cadmium, lead, and
mercury are now known to cause
serious public health problems in
several areas of the world.
Likewise, the geographical
distributions of several infectious
diseases such as malaria,
meningitis, and schistosomiasis,
have been linked to intrinsic
climatic and environmental factors.
Research on this topic dealt with
disease ecology, toxicology,
pathology and/or epidemiology with
regard to the emerging subject of
medical geology.
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Natural Resources Damage
Assessment and Management:
Several environmental influences
including natural and anthropogenic
factors have been linked to
ecosystem vulnerability. Monitoring
and assessment data are therefore
needed for science-based
decision-making with regard to
environmental management. Papers for
presentation on this topic included
those related to: a) conceptual
modeling for ecological risk
assessment, b) assessment of the
physical, chemical, and biological
characteristics of specific
ecosystems, c) applications of GIS
and remote sensing technology to
environmental assessment and
management, and d) bioindicators for
environmental management.
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Major Contributors |
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NCRR - NIH |
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Office
of Research, JSU |
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Office of Academic
Affairs, JSU |

Title III Program |
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National Library
of Medicine |
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